The Committee aims to publish papers where appropriate (except items where data was provided in confidence). These papers have been drafted by the secretariat and do not necessarily represent the veiws of the Committee or government departments. In some cases, the papers are published without the appended references which are subject to copyright of the publishing journals.

2000 2001 2003 2004 2005 2006 2007 2008

2008

CC/08/2 - Second draft working paper on chlorinated drinking water and cancer

CC/08/3 - IPCS Mode of Action Human Relevance Framework

CC/08/6 - Initial discussion paper on the assessment of chemical mixtures

CC/08/7 - Second draft working paper
CC/08/8 - 1,3-butadiene and non-Hodgkin's lymphoma: review of the evidence for IARC's reclassification of 1,3-butadiene to Group 1 carcinogen

CC/08/9 - Revision of OECD test guidelines for carcinogenicity studies

CC/08/10 - Mechanisms contributing to the synergism of alcohol and tobacco in human cancers

CC/08/11 - Excess Mortality in Two-Year Rodent Carcinogenicity Studies

CC/08/12 - Revision of 1981 OECD Test Guidelines TG 451, (Chronic Carcinogenicity Study in Rodents), TG 452 (Long-Term Chronic Toxicity Study in Rodents by Oral Administration) and TG 453 (Combined Chronic Toxicity/Carcinogenicity Studies)

CC/08/13 annex A annex C - Pyrrolizidine Alkaloids in Food - Initial Assessment of Carcinogenicity

CC/08/14 - Proposed strategy for reviewing carcinogen-carcinogen mixtures

CC/08/15 - Update review of "Cancer incidence near municipal solid waste incinerators"

CC/08/16 - First Draft Update Statement on the review of cancer incidence near municipal solid waste incinerators

CC/08/17 - Horizon Scanning 2008

CC/08/18 - Is age an independent risk factor for chemically induced acute myelogenous leukemia in children?

CC/08/19 - Chemical mixtures: the potential for chemical interactions in carcinogenesis?

CC/08/20 - Mechanisms contributing to the synergistic effects of asbestos and tobacco in human lung cancers

CC/08/21 - Preliminary Report by SCHER, SCCP and SCENIHR in "Risk assessement methodologies and approaches for mutagenic and carcinogenic substances"

2007

CC/07/1 - Assessing the risks of acute or short-term exposure to carcinogens

CC/07/3 - Draft Working Paper on Prostate Cancer and Pesticide Exposure

CC/07/4 - Technical guidance for derivation of DNELs and risk characterisation of non-threshold effect in the context of REACH

CC/07/07 - Non-Hodgkin's review: overview paper

CC/07/08 - Further consideration of the MOE approach for communicating the risks of exposure to genotoxic carcinogens

CC/07/09 - Formaldehyde: an update on current assessment of carcinogenicity

CC/07/10 - Revised Code of Conduct for observers

CC/07/11 - Epidemiological studies of chlorinated drinking water and cancer

CC/07/12 - Toxicogenomics: A selective update of the literature since 2004

CC/07/13 - Folic acid - further papers

CC/07/14 Annex 1 Annex 2 Annex 3 - Further consideration of the MOE approach
CC/07/15 - Draft working paper

CC/07/16 - Paper by Vineis et al (2007) on "Exposure to solvents and risk of non-Hodgkin's lymphoma: Clues on putative mechanisms"

CC/07/17 - Papers on QSAR predictive models for carcinogens

CC/07/18 - Horizon scanning exercise 2007

CC/07/19 - Draft working paper on chlorinated drinking water and cancer

2006

CC/06/01 and convertable plus addiction COC

CC/06/03 - Testicular Cancer - Overview Paper

CC/06/6 - Ramazzini Study on the carcinogenicity os aspartame

CC/06/8 - Age-related differences in the susceptibility of carcinogenesis

CC/06/9 - Revised procedure for holding committee meetings in open session

CC/06/10 - "Tissue Organisation Field Theory" of carcinogenesis

CC/06/12 - "Creative Accounting": Report by People for the Ethical Treatment of Animals (PETA)

CC/06/13 - Initial discussion on comparative risk assessment

CC/06/17 - Ramazzini study on the carcinogenicity of aspartame - Further information

CC/06/18 - Annex 1 CC/93/29 + CC/94/7 - Betel quid, Pan Masala and areca nut chewing

CC/06/19 - Acute T25 - Possible approach to potency ranking of single exposure genotoxic carcinogens

CC/06/20 - Comparative Risk Assessment: Application of the MOE approach for communicating the risks of exposure to genotoxic carcinogens

CC/06/21 - Horizon scanning exercise 2006

CC/06/22 - Annex 2 published by DEFRA PS2609 - Report on prostate cancer and pesticide exposure

2005

CC/05/2 - Carcinogenesis mode of action & human relevance framework

CC/05/3 - Paper by Knox on childhood cancers & atmospheric carcinogens

CC/05/5 - Overview of nanomaterial toxicology

CC/05/6 - Single/short term exposure to carcinogens

CC/05/7 - Expert opinions on trends in childhood cancer incidence

CC/05/8 - Review of the possible associations between childhood leukaemia and residence near sources of traffic exhaust and petrol fumes

CC/05/10 - Cholangiocarcinoma: Pathogenesis in humans and rats

CC/05/12 - Human relevance framework: suggestions for additional work

CC/05/13 - COC response to EFSA Scientific Committee

CC/05/14 - Draft Statement on the review of the possible association between
childhood leukaemia and residence near sources of traffic exhaust and petrol fumes

CC/05/15 - Styrene: Mode of action evaluation: Lung tumours in mice

CC/05/16 - The carcinogenicity of perfluoroalkyl acids - perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)

CC/05/17 - Horizon Scanning 2005

CC/05/18 - Draft Working Paper on Nanomaterial Toxicology

CC/05/19 - Statement of joint meeting 9 June 2005. Use of target organ mutagenicity data in carcinogenic risk assessment

CC/05/20 - Review of the recent data on the quantitative relationship between alcohol consumption and squamous cell carcinoma

CC/05/22 - Carcinogenicity of Furan

CC/05/23 - PFOA

CC/05/24 - Opinion of the Scientific Committee on a request from EFSA related to a Harmonised Approach for Risk Assessment of Substances Which are both Genotoxic and Carcinogenic

2004

CC/04/2 - Prostate Cancer: Additional data and 1st draft statement

CC/04/3 - Organochlorines and risk of breast cancer: Additional Information and 1st draft statement

CC/04/4 - 1,3-Dichloropropanol

CC/04/5 - Gene expression profiling in rats exposed to main stream smoke

CC/04/6 - Gene expression profiling in rats exposed to main stream smoke

CC/04/12 - Prostate Cancer: Occupational exposure to PAHs

CC/04/13 - Prostate Cancer: Review of rubber industry

CC/04/14 - Oesophageal cancer: Initial overview paper

CC/04/15 - Draft COC guidelines: Response to consultation

CC/04/18 - Malachite Green/Leucomalachite green

CC/04/30 - Re-assessment of toxicological testing of tobacco products

CC/04/31 - Childhood Cancer - Overview paper

CC/04/32 - Horizon scanning paper

CC/04/37 - Childhood leukaemia and environmental exposures

2003

CC/03/4 - Organochlorine insecticides and risk of breast cancer

CC/03/18 - Environmental tobacco smoke. Paper by Enstrom JE and Kabat GC, BMJ, vol 326, 1057-1066

CC/03/22 - Horizon scanning (paper from DH Toxicology Unit)

CC/03/23 - Evaluation of dose-response at low dose levels (ED01)

CC/03/25 - Biobank project: presentation by Dr Peter Greenaway

CC/03/35 - Prostate Cancer

Annex to CC/03/35 - Review of Prostate Cancer

CC/03/36 - Prostate Cancer: additional systematic review

CC/03/37 - Olfactory Neuroblastomas: Evidence for association in dental workers? An initial discussion paper

CC/03/38 - Organochlorine Insecticides: Information on oestrogenicity (post 1999)

CC/03/39 - Draft discussion paper on improving openness of COC (November 2003)

CC/03/41 - Organochlorine insecticides: Tabulation/Graphical presentation of epidemiology studies

Annex to CC/033/41 - Beta HCH

Annex to CC/033/41 - DDT
Annex to CC/033/41 - Dieldrin
Annex to CC/033/41 - Graphs Sheet 1
Annex to CC/033/41 - Graphs Sheet 2
Annex to CC/033/41 - Graphs Sheet 3
Annex to CC/033/41 - Graphs Sheet 4
Annex to CC/033/41 - DDE

CC/03/42 - 1,3 Dichloropropan-2-ol (November 2003)

2001

CC/01/3 - Criteria for the design of gene-environment epidemiology studies- Table related to paper CC/01/3

CC/01/4 - A review of potential target genes for susceptibility to carcinogenesis

CC/01/5 - A review of how gene-environment studies should be used in risk assessment process

CC/01/6 - 1,3-dichloropropan-2-ol (1,3 DCP) and 2,3-dichloropropan-1-ol (2,3 DCP)

CC/01/22 - Recent developments, and ECETOC Workshop on proposed uses in chemical carcinogen regulation

CC/01/25 - Minimum duration of carcinogenicity studies

2000

ILSI's Collaborative research program on alternative models for carcinogenicity assessment. Presentation to COC on 24 June 1999 by Dr Denise Robinson (HESI,ILSI) (COC/99/ILSI)

Supporting papers to Alcohol and Breast Cancer statement (COC/00/S4) prepared by the DH Toxicology Unit, Imperial College of Science and Technology: