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Expertise

The template is designed to show the breadth of expertise available to the Committee and is intended to aid members in discussing future needs with regard to expertise necessary to fulfil the terms of reference of the COC. The compliment of COC is 14 members (10 specialists and two lay members), attendance of COM chair (ex-officio capacity) and one chair. A deputy chair has not been appointed.

 

Chair: Leadership, presentation of questions/ referrals to members. representation of COC views to media. Expertise in carcinogenicity evaluation.
1.Questions for committee
Referrals.
2. Advice to CMO/Chair Food Standards, Government Departments;
   
 
Input from or advice to COM/COT on Toxicity or Mutagenicity of chemicals
Committee evaluation of specialist advice. Overall advice on risk of carcinogenicity
 
 
 
Structure
Activity
Relationships,
Carcinogen test strategies
 
Metabolism and activation of chemicals. Use of kinetics in carcinogen risk assessment.
 
Design, interpretation and significance of carcinogenicity tests.
Risk assessment of carcinogens
           
Development of new test methods. Assessment of new methods, e.g
Use of transgenic animal models. Development of novel approaches to epidemiology. Molecular biology of carcinogenesis
 
Provision of lay overview of scientific advice and input to drafting of documents.