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COC Meeting 10th April 2008

Agenda

1. Apologies for absence

2. Minutes of meeting held on 15 November 2007 - CC/MIN/07/3

3. Matters Arising

4. Second draft working paper on chlorinated drinking water and cancer - CC/08/2

5. Mode of Action/Human Relevance Framework:

     5.1 IPCS Mode of Action Human Relevance Framework - CC/08/3

     5.2 Presentation of Project on MOA - Oral presentation

     5.3 Statistical inferences about the mechanism of action in
carcinogenicity studies. Sielken et al (2005) - CC/08/4

6. Revision of OECD test guidelines for carcinogenicity studies - CC/08/9

7. Non-Hodgkin's lymphoma:

     7.1 1,3-butadiene and non-Hodgkin's lymphoma: review of the evidence
     for IARC's reclassification of 1,3-butadiene to Group 1 carcinogen - CC/08/8
     7.2 Second draft working paper - CC/08/7

8. Initial discussion paper on the assessment of chemical mixtures - CC/08/6

9. Carcinogen-DNA adducts as a biomarker for cancer risk. Rundle (2006) - CC/08/5

10. Any other business

11. Dates of next meeting -17 July 2008.

Secretariat
March 2008

NB: Lunch will be provided